After being called to a domestic disturbance at around 2 a.m. local time, ambulance crews treated Phil Walsh, 55, for multiple stab wounds but he died at the scene. The crews alerted the police.
His 26-year-old son, who lived with Walsh and his wife, has been charged with murder. A knife, believed to have been used in the attack, was retrieved from the scene.
Walsh's wife also sustained non-life-threatening injuries and is being treated at the Flinders Medical Centre in the city.
Argument leads to stabbing
"Police were able to establish that, around two o'clock, the son of the family had attended, there had been an argument... as a result of that Mr. Walsh and his wife received the wounds," Superintendent Des Bray, Officer in Charge, Major Crime Detectives, told reporters.
Walsh's son was arrested on a street around 2.5 km (1.5 miles) a short time later and is being detained, also at Flinders, for a psychiatric assessment.
